TotalRx is the best-value way to start a GLP-1 that we have reviewed. Most programs advertise a low first month and a higher price afterwards, or add a membership fee to the medication. TotalRx does neither. The rate you start on is the rate you keep, and it includes the clinician, the medication, shipping and ongoing support.
If you are paying out of pocket and plan to stay on treatment long enough to see real results, it is the one we recommend first.
What TotalRx gets right
A price that never goes up
Your monthly rate is locked for as long as you stay. No introductory price that jumps at renewal, which is where most of this market makes its money.
No membership fee
Several well-known programs charge around $149 a month for membership before medication. TotalRx's compounded plans are one flat price.
Care is included, not upsold
Clinician review, dose adjustments and unlimited check-ins are part of the plan. You are not billed per visit or per message.
Both leading medications
Choose compounded semaglutide or tirzepatide, with dosing set and adjusted by a licensed clinician rather than left to you.
No insurance, no paperwork
Flat cash pricing means no prior authorization and no surprise bills. HSA and FSA cards are accepted.
Delivered free
Medication ships from a licensed US pharmacy in discreet packaging at no extra cost, with refills timed to arrive before you run out.
Is TotalRx legit?
Yes. TotalRx is a legitimate US telehealth service, not a grey-market seller. It is operated by Coravita Health, LLC, and it works the way a properly run GLP-1 program should: a licensed clinician has to approve you before any medication is dispensed, and a licensed pharmacy fills the prescription.
- Real prescriptions. Every order is reviewed by a US-licensed clinician in your state.
- Licensed pharmacies. Medication is prepared and shipped by state-licensed US compounding pharmacies.
- Prices in the open. Plan and renewal prices are shown before you pay.
- Published policies. Refund, cancellation, privacy and safety information are all on its website.
- Your data is protected. Health information is handled under HIPAA.
- A refund if you are not approved. You are not left paying for treatment you cannot have.
The signs of a scam in this market are no prescription, no clinician, and prices that change after you pay. TotalRx is the opposite on all three, which is a large part of why it tops our rankings.
How TotalRx works
The whole process is online and most people finish the first two steps in under ten minutes.
- About 2 minutesTake the free assessmentAnswer questions about your health history, current medications and goals. There is nothing to upload and no appointment to book.
- About 3 minutesChoose your planPick semaglutide or tirzepatide and a plan length. The full price and the renewal price are shown before you pay.
- Usually within 24 hoursA licensed clinician reviews your caseA clinician licensed in your state confirms treatment is right for you and sets your starting dose. If it is not right for you, you are refunded in full.
- Typically 3 to 5 daysMedication arrives at your doorShipped free from a licensed US pharmacy. Message your care team whenever you have a question or need a dose change.
What TotalRx costs
Every plan below is locked for life: whichever one you pick, that monthly rate does not rise at renewal. Longer plans cost less per month and are paid for the term up front.
| Plan | Compounded semaglutide | Compounded tirzepatide |
|---|---|---|
| 12 months Best value | $129/mo | $174/mo |
| 6 months | $139/mo | $189/mo |
| 3 months | $149/mo | $199/mo |
| Month to month | $199/mo | $249/mo |
For comparison, a program charging a $149 monthly membership plus medication typically comes to around $298 a month. On the 12-month plan TotalRx is less than half that, and the gap widens every time a competitor's renewal price goes up and TotalRx's does not.
TotalRx semaglutide vs tirzepatide
TotalRx offers both of the leading GLP-1 medications as a once-weekly injection. Your clinician helps you choose, and you can ask about switching later.
TotalRx semaglutide
From $129/mo. The most widely prescribed GLP-1 and the lowest-cost way to start.
- Same active ingredient as Wegovy® and Ozempic®
- About 15% average weight loss in the brand-name STEP-1 trial
- Best for: most people starting out
TotalRx tirzepatide
From $174/mo. Acts on two hormone pathways, GLP-1 and GIP.
- Same active ingredient as Zepbound® and Mounjaro®
- About 20% average weight loss in the brand-name SURMOUNT-1 trial
- Best for: people with more to lose, or who have plateaued
Trial results are for the brand-name medications alongside diet and exercise. Individual results vary.
TotalRx vs other GLP-1 providers
The difference shows up once you look past the first month. This is how TotalRx compares with the typical membership-based program.
| TotalRx | Typical membership program | |
|---|---|---|
| Semaglutide, monthly cost | From $129 | Around $298 with membership |
| Membership fee | None | About $149/mo |
| Price at renewal | Locked for life | Can increase |
| Clinician follow-ups | Unlimited, included | Varies |
| Insurance needed | No | Sometimes |
| Shipping | Free | Varies |
See every provider side by side in our full 2026 rankings.
What to know before you sign up
No program is perfect for everyone. These are the questions readers ask most, and how TotalRx answers them.
Is TotalRx safe? Side effects to expect
GLP-1 medications are well studied, and TotalRx prescribes them the standard way: starting at a low dose and increasing gradually under a clinician's supervision. That approach is what keeps side effects manageable for most people.
The most common side effects are digestive: nausea, constipation, diarrhea and occasional vomiting. They usually appear when a dose goes up and ease as your body adjusts. Because check-ins are unlimited, you can message your care team as soon as something feels off and have your dose adjusted.
GLP-1s are not suitable for everyone, including people who are pregnant or have a personal or family history of certain thyroid cancers. That is what the health assessment and clinician review are for. Read TotalRx's Important Safety Information before you start.
Cancelling, refunds and customer service
How to cancel TotalRx
You can cancel at any time through your online account or by contacting support. Cancel at least 72 hours before your billing date and you will not be charged again.
TotalRx refund policy
If a clinician decides treatment is not right for you, you receive a full refund. On multi-month plans, months that have not yet been shipped can be refunded pro rata if you stop early. As with any pharmacy, medication that has already been dispensed cannot be returned.
TotalRx customer service
Members message their care team through the patient portal, and TotalRx says the team is available around the clock for questions and dose adjustments. Billing and account questions go through the contact page on totalrx.com.
TotalRx promo codes and discounts
You do not need a coupon code. The price-for-life rates on this page are applied automatically when you start through our link, and they are lower than the standard monthly price.
Who TotalRx is best for
- You are paying out of pocket and want the lowest long-term cost.
- You are tired of prices that climb after the first month.
- You want a clinician involved, with support included rather than charged per visit.
- You would rather do everything online, with medication delivered.
- You want to use HSA or FSA funds.
TotalRx reviews: your questions answered
Is TotalRx legit?
Yes. TotalRx is a US telehealth service operated by Coravita Health, LLC. Prescriptions are written by US-licensed clinicians and filled by state-licensed US pharmacies.
Is TotalRx a scam?
No. You are assessed by a licensed clinician, prices are shown before you pay, and you are refunded in full if you are not approved for treatment.
Is TotalRx safe?
TotalRx follows standard GLP-1 prescribing: a clinician reviews your health history, starts you on a low dose and adjusts it over time. Compounded medications are not FDA-approved, so read the safety information and talk to your clinician about any concerns.
How much does TotalRx cost?
Compounded semaglutide starts at $129 a month and compounded tirzepatide at $174 a month on a 12-month plan. Month-to-month plans are $199 and $249. Every plan is locked at its starting price for life.
Does TotalRx have a membership fee?
No. The compounded plans are one flat price that includes the clinician, medication, shipping and follow-ups.
Does TotalRx take insurance?
TotalRx is a cash-pay service, so no insurance or prior authorization is needed. HSA and FSA cards are accepted, and a Letter of Medical Necessity is available once you are prescribed.
Is there a TotalRx promo code?
No code is needed. The price-for-life rates are applied automatically through our link.
Is TotalRx semaglutide the same as Ozempic or Wegovy?
It contains the same active ingredient, semaglutide, but it is a compounded medication rather than the brand-name product, and compounded medications are not FDA-approved.
Does TotalRx offer tirzepatide?
Yes, compounded tirzepatide from $174 a month, as a once-weekly injection.
How long does TotalRx take to ship?
TotalRx says clinicians usually review within 24 hours and medication typically arrives 3 to 5 days after it is prescribed. Shipping is free.
How do I cancel TotalRx?
Through your online account or by contacting support, at any time. Cancel at least 72 hours before your next billing date to avoid the next charge.
Can I get a refund from TotalRx?
You get a full refund if a clinician finds you are not eligible. On multi-month plans, unshipped months can be refunded pro rata. Medication that has already shipped cannot be refunded.
Who owns TotalRx?
TotalRx is a brand of Coravita Health, LLC, a US company.
Who is eligible for TotalRx?
Adults who meet the clinical criteria for GLP-1 treatment, generally a BMI of 30 or more, or 27 or more with a weight-related condition. The free assessment tells you in about two minutes.
What does "price for life" mean?
The monthly rate you start on is the rate you keep at every renewal for as long as you stay, with no membership fee added.
Can I switch between semaglutide and tirzepatide?
Your clinician decides what is appropriate, and many people do switch. Ask your care team how it affects your plan.
Ready to try TotalRx?
Semaglutide from $129 a month, tirzepatide from $174. One price, locked for life, with care and shipping included.
Try TotalRx Today Free 2-minute assessment · No insurance requiredHow we review. This review is based on TotalRx's published pricing, plan terms and policies as of October 11, 2026, scored on the same five factors as every provider in our rankings. Medical disclaimer. This page is general information, not medical advice. Consult a licensed healthcare professional before starting any medication. Compounded GLP-1 medications are not FDA-approved and do not undergo the same review for safety, effectiveness and quality as brand-name products. Individual results vary. Prices can change; confirm them with TotalRx before you pay. Third-party names are trademarks of their owners.