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TrumpRx and GLP-1s: what the site does, what it costs and whether it helps you

TrumpRx.gov is a government website that lists brand-name drug prices for people paying cash, including the GLP-1s Wegovy®, Ozempic® and Zepbound®. It is useful, but it is often misunderstood. It is not a pharmacy and it does not have its own discount. Here is what it actually does.

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The short answer

What TrumpRx actually is

TrumpRx.gov went live on February 5, 2026, listing 43 brand-name drugs from five manufacturers 2. It came out of agreements announced in November 2025, under which drug makers agreed to offer lower cash prices to Americans paying out of pocket 3. For each drug, the site shows the lowest cash price and sends you to the manufacturer's own program, such as LillyDirect for Zepbound® or NovoCare Pharmacy for Wegovy®, to complete the purchase 1.

So TrumpRx is best understood as a signpost. It brings the manufacturers' cash prices together in one place, which is genuinely handy, but it does not add a discount of its own.

GLP-1 prices on TrumpRx, and what they leave out

The site shows one "from" price per drug. That is the cheapest dose or an introductory rate, and you will pay more once your dose goes up:

MedicationListed on TrumpRxWhat you will usually pay later
Wegovy® pill$149/mo$199 at 4 mg, $299 at 9 and 25 mg 5
Wegovy® pen$199/mo$349 after the first two fills; $399 at 7.2 mg 5
Ozempic®$199/moHigher after the introductory period; confirm with NovoCare
Zepbound®$299/mo$399 at 5 mg; $449 at 7.5 mg and up if refilled within 45 days, otherwise $499 to $699 4

TrumpRx prices read October 19, 2026 1. Ozempic® is approved for type 2 diabetes and is prescribed off-label for weight loss.

Compared with the list prices these drugs carried a couple of years ago, often more than $1,000 a month, these are big reductions. But a usual dose of Zepbound® still costs about $449 a month, or roughly $5,200 in a first year.

Experts on whether TrumpRx will lower drug pricesCBS News, February 2026. A short report on what the site lists and who it is likely to help.
TrumpRx explained for GLP-1 usersBeyond the Scale, February 2026. A patient-educator walks through the GLP-1 prices on TrumpRx and who actually saves.

How buying through TrumpRx works

  1. Get a prescription. From your own doctor or a telehealth provider. TrumpRx does not prescribe.
  2. Find the drug on TrumpRx.gov and follow the link to the manufacturer's program.
  3. Buy through the manufacturer's pharmacy or partner, which checks your prescription and ships it or sends it to a pharmacy.

Because the site hands you on to the manufacturer, you can skip TrumpRx entirely and go straight to LillyDirect or NovoCare if you prefer. The price is the same.

Who TrumpRx is not for

TrumpRx vs a telehealth program vs compounded

TrumpRx (via manufacturer)Membership telehealth programCompounded program
MedicationFDA-approved brand-nameFDA-approved brand-nameCompounded, not FDA-approved
PrescriptionBring your ownIncludedIncluded
Typical monthly cost at the usual dose$299 to $449$448 to $598 with a $149 membershipAbout $129 to $300
Ongoing clinical supportFrom your own doctorIncluded in membershipUsually included

If you already have a doctor willing to prescribe and you want brand-name medication, buying at the manufacturer's price, through TrumpRx or directly, is the cheapest brand-name route. If you need a prescriber as well, a telehealth program adds its fee on top. If cost is the deciding factor and you are comfortable with a compounded medication, programs such as TotalRx, our #1 pick at $129 a month on a 12-month plan, cost less again. Our compounded vs brand-name guide explains that choice.

Questions and answers

What is TrumpRx?

TrumpRx.gov is a federal website, launched in February 2026, that lists cash prices for brand-name drugs from participating manufacturers and links to where you can buy at those prices. It does not dispense or sell medication itself.

How much is Zepbound on TrumpRx?

TrumpRx lists Zepbound® from $299 a month. That is Lilly's self-pay price for the 2.5 mg starting dose; higher doses cost $399 to $449 a month, or more if a refill is late.

How much is Wegovy on TrumpRx?

The Wegovy® pill is listed from $149 a month and the Wegovy® pen from $199. The pill rises to $299 at the higher doses, and the $199 pen price is an introductory rate for the first two fills, after which it is $349.

Is TrumpRx cheaper than LillyDirect or NovoCare?

No. TrumpRx sends you to those same manufacturer programs, so the price is the same.

Do I need a prescription to use TrumpRx?

Yes. These are prescription medications, so you need a valid prescription from a licensed clinician, either your own doctor or a telehealth provider.

Can I use TrumpRx if I have Medicare?

The manufacturer cash offers it links to exclude people on government programs. Medicare members should look at the Medicare GLP-1 Bridge, which costs $50 a month for those who qualify.

Does TrumpRx count toward my insurance deductible?

No. Purchases are cash-pay and are not counted toward an insurance deductible or out-of-pocket maximum.

Sources

  1. TrumpRx.gov
  2. Axios: TrumpRx drug price site goes live (February 6, 2026)
  3. The White House: fact sheet on most-favored-nation pricing deals (November 2025)
  4. Eli Lilly: Zepbound® coverage, savings and self-pay prices
  5. NovoCare Pharmacy: Wegovy® self-pay prices
  6. CMS: Medicare GLP-1 Bridge